Napoli has kept a clean sheet in four of their last six Serie A meetings against Genoa.
Dries Mertens is set to be rested after picking up a knock in midweek.
Napoli have made huge changes after European games this term, and that should continue her
Krzysztof Piatek is doubt
Genoa Possible Starting lineup:
Radu (GK), Biraschi, Zukanović, Criscito, Pereira, Rômulo, Veloso, Lazović, Bessa, Kouamé, Piątek
Napoli Possible Starting lineup:
Ospina (GK), Hysaj, Albiol, Koulibaly, Rui, Allan, Hamšík, Ruiz; Callejón, Mertens, Insigne